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. 2021 Nov 19;18(4):2337–2350. doi: 10.1007/s13311-021-01153-z

Table 1.

WHO recommendations for multi-drug treatment of Hansen’s disease

WHO
Drugs Paucibacillary Multibacillary
Dapsone Adult 100 mg daily 100 mg daily
Child (10–14 yrs.) 50 mg 50 mg
Child under 10 25 mg 25 mg
Rifampin Adult 600 mg once/month 600 mg once/month
Child (10–14 yrs.) 450 mg once/month 450 mg once/month
Child under 10 300 mg once/month 300 mg once/month
Clofazimine Adult 50 mg daily plus 300 mg once/month
Child (10–14 yrs.) 50 mg daily plus 150 mg once/month
Child under 10 50 mg twice a week and 100 mg once a month
Duration (months) 6 doses (6 blisters) that can be taken until 9 months 12 doses (12 blisters) that can be taken until 9 months

In the USA, PB patients are treated with rifampin 600 mg and dapsone 100 mg daily for 12 months. MB patients are treated with rifampin 600 mg, clofazimine 50 mg daily, and dapsone 100 mg for 24 months