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. 2021 Nov 12;2021:3827501. doi: 10.1155/2021/3827501

Figure 1.

Figure 1

Lidocaine significantly alleviated sepsis-induced acute lung injury. Survival rate (a) and body weight (b) of mice were measured every day for 7 consecutive days (n = 12 of each group). (c) Wet/dry weight of mouse lung tissues was measured 12 h after intraperitoneal (i.p.) injection of 12.5 mg/kg LPS to mice. (d) Representative images of B-mode ultrasound. Normal mice show an “A” line, while “B” line indicates pulmonary edema in mice. (e) Total protein concentration in bronchoalveolar lavage fluid (BALF). (f) Neutrophil proportion in the blood assessed by flow cytometric analysis. (g) Quantitative data of the neutrophil proportion analyzed by flow cytometry. (n = 4 of each group). Significant difference was revealed following one-way or two-way ANOVA (∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 vs. control; #P < 0.05, ##P < 0.01, and ###P < 0.001 vs. LPS-treated group; Bonferroni post hoc tests).