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. 2021 Nov 12;2021:3827501. doi: 10.1155/2021/3827501

Figure 5.

Figure 5

Lidocaine significantly induced expression of p-AMPK and SOCS3 both in vivo and in vitro. (a, b) Representative Western blot images showed the levels of p-AMPK and SOCS3 in lung tissues from mice given different dosages of lidocaine (2, 4, and 8 mg/kg, i.v.) 30 min before LPS injection (n = 4 of each group). (c, d) Representative Western blot bands have shown the level of p-AMPK and SOCS3 in THP1 cells cultured with different concentrations of lidocaine for 6 h. Significant difference was revealed following one-way ANOVA (∗P < 0.05 and ∗∗P < 0.01 vs. control; Bonferroni post hoc tests).