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. 2021 Nov 12;2021:8936865. doi: 10.1155/2021/8936865

Table 1.

Characteristics of included studies.

First author Publication year Country Population Age (control vs. intervention) Sample size (control vs. intervention) Type of study Type of intervention Control group Duration
Fan et al. 2013 China NAFLD + T2DM + obesity 54.68 ± 12.14; 51.02 ± 10.10 68/49 RCT Exenatide Metformin 12 weeks

Shao et al. 2014 China NAFLD + T2DM 42 ± 3.2; 43 ± 4.1 30/30 RCT Exenatide + insulin glargine Insulin aspart + insulin glargine 12 weeks

Armstrong et al. 2016 UK NASH with/without T2DM 18–70 7/7 Double-blind, randomized, placebo-controlled trial Liraglutide Placebo 12 weeks

Armstrong et al. 2016 UK NASH with/without T2DM 50 ± 12; 50 ± 11 22/23 Multicentre, double-blinded, randomized, placebo-controlled phase 2 trial Liraglutide Placebo 48 weeks

Khoo et al. 2017 Singapore NAFLD + obesity 43.7 ± 10.4; 39.0 ± 8.1 12/12 Pilot randomized trial Liraglutide Diet + exercise 26 weeks

Wang et al. 2017 China NAFLD + T2DM 40–78; 41–75 49/49 RCT Exenatide + metformin Metformin 12 weeks

Feng et al. 2017 China NAFLD + T2DM 48.07 ± 12.59; 46.79 ± 9.68 29/14.5 Single-center, open-label, prospective, and randomized trial with parallel design Liraglutide Gliclazide 24 weeks

Feng et al. 2017 China NAFLD + T2DM 46.31 ± 12.32; 46.79 ± 9.68 29/14.5 Single-center, open-label, prospective, and randomized trial with parallel design Liraglutide Metformin 24 weeks

Tian et al. 2018 China NAFLD + T2DM 56.4 ± 8.4; 58.5 ± 7.6 75/52 RCT Liraglutide Metformin 12 weeks

Yan et al. 2019 China NAFLD + T2DM 45.7 ± 9.2; 43.1 ± 9.7 27/12 Randomized, open-label, active-controlled, parallel-group, multicenter trial Liraglutide Sitagliptin 26 weeks

Yan et al. 2019 China NAFLD + T2DM 45.6 ± 7.6; 43.1 ± 9.7 24/12 Randomized, open-label, active-controlled, parallel-group, multicenter trial Liraglutide Insulin glargine + metformin 26 weeks

Khoo et al. 2019 Singapore NAFLD 43.6 ± 9.9; 38.6 ± 8.2 15/15 Prospective randomized pilot study Liraglutide Diet + exercise 26 weeks