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. 2021 Nov 15;15:4687–4699. doi: 10.2147/DDDT.S329507

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© 2021 Lu et al.

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A rat model of IC/BPS was successfully established by administration of CYP. Analysis was performed 4, 24, and 48 h after intraperitoneal injection of saline or CYP. (A) The bladder weight to body weight ratio (n=6). (B) HE staining of bladder sections from saline- and CYP-treated rats. The stars indicate epithelial ulceration, the arrows indicate submucosal haemorrhaging, and the triangles indicate infiltration of inflammatory cells. Student's t-test was for statistical analysis. ***P<0.001.