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CYP successfully induced hyperalgesia and bladder overactivity 4, 24, and 48 h after intraperitoneal injection of saline or CYP. (A) The change in the PWT (n=6). The basal PWT at 0 h was defined as 100%. (B) Representative cystometrogram traces and (C–E) statistical analysis of the micturition interval, basal bladder pressure, and maximum bladder pressure (n=5). Student's t-test was used for statistical analysis. *P<0.05; **P<0.01; ***P<0.001; ns, no significance.
