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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Genet Epidemiol. 2021 Jul 10;45(8):811–820. doi: 10.1002/gepi.22424

Table 4.

AUCs of different methods based on AnnoPred for Crohn’s disease and type 2 diabetes in the meta-GWAS studies.

Trait AnnoPred AnnoPred+STRS (p-valuea) AnnoPred+MTRS (p-valueb)
Crohn’s disease 0.7023 0.7061 (2.924 × 10−4) 0.7083 (1.888 × 10−5)
Type 2 diabetes 0.6302 0.6354 (0.002) 0.6377 (3.940 × 10−4)

Abbreviations: AUC, area under the curve; STRS, single-tissue transcriptional risk score; MTRS, multi-tissue transcriptional risk score.

a

p-value is based on the bootstrap test of comparing AnnoPred+STRS with AnnoPred across 100 stratified bootstrap replicates.

b

p-value is based on the bootstrap test of comparing AnnoPred+MTRS with AnnoPred across 100 stratified bootstrap replicates.