Figure 6.

Analysis of the lipidome of CD9⁺and Ly6C⁺adipose-tissue-resident macrophages from high-fat-fed mice.A, principal components analysis (PCA) of the global lipidome. B, TG levels in CD9⁺ and Ly6C⁺ macrophages. C, heat map showing significantly different neutral loss (NL) TG species. Phospholipid—total PC (D), diacyl-PC (E), ether-PC (F), total PE (G), diacyl-PE (H), ether-PE (I), PI (J), PS (K); and sphingolipid—ceramide (L), hexosyl-ceramide (M), and sphingomyelin (N) levels in CD9⁺ and Ly6C⁺ macrophages. In (B and D–N), data was analyzed by unpaired t test with exact p values indicated. Data are shown as mean ± S.D. (error bars) as well as with individual data points from each biological replicate.