Figure 2:

Results of network-based pathway enrichment analysis based on a breast cancer data set. $p$-values ($-{\mathrm{l}\mathrm{o}\mathrm{g}}_{10}$ scale) of t-tests for group difference of each gene pathway: a - compare REHE results against REML results; b - compare reREHE results against REML results. Two out-of-range data points are omitted from the plots, which correspond to: Glycosphingolipid biosynthesis - lacto and neolacto series pathway, with $p$-value $1.09\times {10}^{-307}$ by REML, $5.67\times {10}^{-276}$ by REHE, $3.74\times {10}^{-304}$ by reREHE; and Caffeine metabolism pathway with $p$-value $3.97\times {10}^{-201}$ by REML, $2.60\times {10}^{-179}$ by REHE, and $2.13\times {10}^{-198}$ by reREHE.