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. 2021 Nov 19;11:22578. doi: 10.1038/s41598-021-01842-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Immune response differential transcript abundances following relevant sporozoite infections. Immune response transcripts that were present at significantly higher (blue) or lower (yellow) levels in Plasmodium falciparum sporozoite infected treatments; non-differentially expressed immune response transcripts are denoted as zeros (black). Immune response genes within each group organized by adjusted p-value and subsequently arrayed left to right from most abundant to least abundant based on FPKM values (quartile bars above each image). (A) Toll and spaetzle proteins (SPZ). (B). IMD and JAK-STAT proteins. Log₂ scale indicates transcript abundances that were significantly higher (blue) or lower (yellow) in sporozoite infected treatments (Trt) vs. naïve controls (Cnt).