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. 2021 Nov 19;5:97. doi: 10.1038/s41698-021-00236-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a, b Representative IHC images and quantification of indicated protein expressions show higher expression in the CFR^High group in UUS (a) and in ESS patients (b). Scale bars indicate 100 μm. c, d Representative IHC images of YAP expression and quantification of its nuclear/cytoplasmic ratio shows a higher ratio in the CFR^High patient group in UUS (c) and in ESS patients (d). Upper panels scale bars indicate 100 μm and lower panels scale bars indicate 20 μm. Plots indicate average ± s.d. Significance test is indicated *(P < 0.05), **(P < 0.01).