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. 2021 Nov 19;11:22602. doi: 10.1038/s41598-021-01860-9

Table 2.

Hazard ratio of hemodialysis, hospitalization, and mortality in patients with CKD stages 3–5 in the pay for performance program in the cox model with competing risks.

Variables HD Hospitalization Mortality
Adjusted HR 95% CI P Adjusted HR 95% CI P Adjusted HR 95% CI P
P4P
Without Reference Reference Reference
With 0.775 0.755–0.807  < .001* 0.800 0.775–0.824  < .001* 0.804 0.775–0.833  < .001*
CKD stage
3 Reference Reference Reference
4 1.888 1.118–2.124  < .001* 2.011 1.317–2.628  < .001* 2.436 1.359–3.190  < .001*
5 3.033 4.049–4.172  < .001* 2.789 1.662–3.849  < .001* 4.498 2.599–7.066  < .001*
Gender
Male 0.919 0.899–0.939  < .001* 0.871 0.850–0.891  < .001* 1.203 1.165–1.240  < .001*
Female Reference Reference Reference
Age (years)
 < 50 Reference Reference Reference
50–59 1.151 1.089–1.217  < .001* 0.919 0.874–0.967 .001* 1.019 0.938–1.109 0.831
60–69 1.279 1.133–1.347  < .001* 0.932 0.889–0.978 .012* 1.191 1.101–1.288  < .001*
70–79 1.455 1.383–1.530  < .001* 0.944 0.902–0.988 .019* 1.766 1.639–1.900  < .001*
80–89 1.380 1.311–1.452  < .001* 0.784 0.747–0.821  < .001* 1.819 1.689–1.960  < .001*
 ≥ 90 0.997 0.925–1.074 .674 0.450 0.413–0.492  < .001* 1.444 1.307–1.594  < .001*
DM
Without Reference Reference Reference
With 0.916 0.890–0.944  < .001* 1.177 1.137–1.219  < .001* 0.854 0.820–0.890  < .001*
HT
Without Reference Reference Reference
With 0.787 0.763–0.800  < .001* 0.304 0.294–0.314  < .001* 0.503 0.486–0.521  < .001*
Hospitalization
Without Reference Reference Reference
With 0.437 0.393–0.487  < .001* 0.710 0.639–0.789  < .001* 0.107 0.077–0.151  < .001*
Stroke
Without Reference Reference Reference
With 1.006 0.958–1.057 .702 0.982 0.929–1.038 0.265 1.242 1.167–1.322  < .001*
CAD
Without Reference Reference Reference
With 1.047 0.999–1.084 .050 0.997 0.960–1.037 0.478 1.051 0.998–1.102 0.052
HF
Without Reference Reference Reference
With 0.975 0.937–1.012 .124 0.896 0.857–0.936  < .001* 1.163 1.104–1.225  < .001*
PVD
Without Reference Reference Reference
With 0.915 0.878–0.955 .003* 0.674 0.641–0.710  < .001* 0.999 0.947–1.056 0.624
Chronic pulmonary disease
Without Reference Reference Reference
With 1.478 1.418–1.540  < .001* 1.072 1.029–1.118 .007 1.446 1.370–1.528  < .001*
Chronic liver disease
Without Reference Reference Reference
With 1.179 1.133–1.228  < .001* 1.000 0.958–1.045 0.612 0.825 0.774–0.879  < .001*
Dementia
Without Reference Reference Reference
With 0.789 0.727–0.855  < .001* 0.655 0.593–0.725  < .001* 0.714 0.636–0.801  < .001*

Adjusted HR: Adjusted variables listed in the table.

*P < 0.05; statistical significance.

Abbreviations CAD = coronary artery disease; CI = confidence interval; CKD = chronic kidney disease; DM = diabetes mellitus; HD = hemodialysis; HR = hazard ratio; HT = hypertension; HF = heart failure; PVD = peripheral vascular disease; P4P = pay for performance program.