Table 2.

Traits with a negative genetic correlation and significant partial causality on ADHD risk.

Trait	GCP	GCP se	GCP pval	rG	rG se	rG pval
High-density lipoprotein (HDL)	− 0.87	0.10	3.86E−19	− 0.27	0.06	1.23E−06
Doing unpaid or voluntary work	− 0.78	0.16	1.96E−06	− 0.59	0.10	1.66E−08
Never been injured or injured someone else through drinking alcohol	− 0.74	0.18	4.70E−05	− 0.42	0.18	1.76E−02
Reduced smoking as a health precaution	− 0.70	0.19	2.77E−04	− 0.38	0.15	1.28E−02
School teacher or teaching professional	− 0.69	0.20	5.28E−04	− 0.26	0.11	1.49E−02
Primary and nursery education teaching professionals	− 0.66	0.21	2.17E−03	− 0.26	0.11	1.63E−02

This table shows significant (FDR < 5%) traits with a robust genetic causal proportion (|GCP| > 0.60) and a negative genetic correlation with ADHD. Trait Trait causally associated with ADHD, GCP Genetic causal proportion, GCP se Genetic causal proportion standard deviation, Genetic causal proportion, GCP pval Genetic causal proportion p-value before FDR correction, r_G Genetic correlation, r_G se Genetic correlation standard deviation, r_G p val Genetic correlation p-value before FDR correction. P-values after FDR correction are available for all traits in Supplementary File 1.