Table 1.
Summary of sites included in the study, number of patients, and local cluster and quiet period definitions.
Location | Patients | Years | Local cluster definition (# of KD cases in 7 days) | Number of clusters | # of patients in clusters | Fraction of patients in clusters | Local quiet period definition (# days with no KD cases) | Number of quiet periods |
---|---|---|---|---|---|---|---|---|
Bay Area, CA USA | 822 | 16 | 4 | 33 | 180 | 0.21 | 9 | 146 |
Boston, MA USA* | 1017 | 18 | 4 | 43 | 223 | 0.22 | 15 | 96 |
DC, USA | 193 | 5 | 4 | 8 | 44 | 0.23 | 9 | 41 |
Denver CO, USA | 629 | 13 | 4 | 30 | 179 | 0.28 | 11 | 99 |
Emilia-Romagna, IT | 502 | 18 | 3 | 36 | 139 | 0.28 | 16 | 121 |
Hawaii, USA | 403 | 11 | 4 | 10 | 48 | 0.12 | 14 | 72 |
Los Angeles, CA USA | 1603 | 16 | 6 | 53 | 458 | 0.29 | 5 | 229 |
New Zealand | 1008 | 19 | 4 | 54 | 274 | 0.27 | 14 | 110 |
Seoul, Korea | 1205 | 13 | 6 | 31 | 257 | 0.21 | 7 | 123 |
San Diego, CA USA | 1332 | 18 | 5 | 47 | 315 | 0.24 | 8 | 177 |
Seattle, WA USA | 646 | 17 | 4 | 22 | 112 | 0.17 | 18 | 80 |
Wakayama Prefecture, Japan | 2255 | 20 | 6 | 76 | 619 | 0.27 | 6 | 209 |
Bold indicates use of the 99.5th percentile as a definition for either cluster or quiet period; black indicates use of 97.5th percentile. We used the more conservative cluster definition in lower incidence areas because an integer value (e.g., 2 cases in 7 days) might span a large percentile range of the distribution of densities in a low-incidence area. We used the higher threshold to define quiet periods in higher incidence regions by a similar logic, to ensure we had used tail values when constrained to use integer values (*The full record from Boston included 1596 patients over 35 years, with 293 patients in 58 clusters, or 18%, and 213 quiet periods. For the analysis here we restricted analysis to after 2000).