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. 2021 Nov 19;11:22584. doi: 10.1038/s41598-021-01961-5

Table 1.

Summary of sites included in the study, number of patients, and local cluster and quiet period definitions.

Location Patients Years Local cluster definition (# of KD cases in 7 days) Number of clusters # of patients in clusters Fraction of patients in clusters Local quiet period definition (# days with no KD cases) Number of quiet periods
Bay Area, CA USA 822 16 4 33 180 0.21 9 146
Boston, MA USA* 1017 18 4 43 223 0.22 15 96
DC, USA 193 5 4 8 44 0.23 9 41
Denver CO, USA 629 13 4 30 179 0.28 11 99
Emilia-Romagna, IT 502 18 3 36 139 0.28 16 121
Hawaii, USA 403 11 4 10 48 0.12 14 72
Los Angeles, CA USA 1603 16 6 53 458 0.29 5 229
New Zealand 1008 19 4 54 274 0.27 14 110
Seoul, Korea 1205 13 6 31 257 0.21 7 123
San Diego, CA USA 1332 18 5 47 315 0.24 8 177
Seattle, WA USA 646 17 4 22 112 0.17 18 80
Wakayama Prefecture, Japan 2255 20 6 76 619 0.27 6 209

Bold indicates use of the 99.5th percentile as a definition for either cluster or quiet period; black indicates use of 97.5th percentile. We used the more conservative cluster definition in lower incidence areas because an integer value (e.g., 2 cases in 7 days) might span a large percentile range of the distribution of densities in a low-incidence area. We used the higher threshold to define quiet periods in higher incidence regions by a similar logic, to ensure we had used tail values when constrained to use integer values (*The full record from Boston included 1596 patients over 35 years, with 293 patients in 58 clusters, or 18%, and 213 quiet periods. For the analysis here we restricted analysis to after 2000).