Table 3:

Physical Function Responder Analysis by Weight Loss at 6 and 12 months

	< 5% Weight loss n (%)	≥ 5% Weight loss n (%)	P value**	Total
Physical Function Status at 6 months*	N = 55	N = 28		N = 83
Improved	10 (18.2)	14 (50.0)	0.004	24 (28.9)
Stable	32 (58.2)	13 (46.4)		45 (54.2)
Worsened	13 (23.6)	1 (3.6)		14 (16.9)
Physical Function Status at 12 months*	N = 43	N = 25		N = 68
Improved	7 (16.3)	10 (40.0)	0.05	17 (25.0)
Stable	27 (62.8)	13 (52.0)		40 (58.8)
Worsened	9 (20.9)	2 (8.0)		11 (16.2)

^*Participants were grouped into 3 categories based on changes in NIH PROMIS Version 1.0 Short Form physical function: Improved (score increase of 5 or more), Stable (score change of less than 5) and Worsened (score decrease of 5 or more)

^**P value for Fisher’s exact test for differences in the distribution of change in physical function at 6 months and 12 months between groups defined according to weight loss