Figure 2.

A comparison of F-propranolol binding to β₂AR in membranes, DDM, and DIBMALPs

(A–C) Representative F-propranolol (2–666 nM) equilibrium saturation plots showing total and non-specific binding to the β₂AR in (A) HEK cell membranes, (B) DDM, and (C) DIBMALPs, n = 1.

(D–F) Saturation binding curves showing specific binding and associated affinity (pK_d) values for F-propranolol binding to the β₂AR in (D) HEK cell membranes, (E) DDM, and (F) DIBMALPs; curves show combined normalized data mean ± SEM, n = 3.