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. 2021 Sep 24;35(11):e23989. doi: 10.1002/jcla.23989

FIGURE 1.

FIGURE 1

Potential downstream regulatory mechanisms of miR‐802. MiR‐802 influences downstream targets as well as (A) the Wnt/β‐catenin pathway, (B) the PI3K/AKT signaling pathway, (C) Hedgehog (Hh) pathway, (D) the EMT signaling pathways, and (E) other mechanisms, thereby affecting proliferation, invasion, metastasis, and apoptosis of tumor cells. ↑, promotion; ↓, inhibition; BC, breast cancer; CC, cervical cancer; CRC, colorectal cancer; CRC, colorectal cancer; EMT, epithelial‐mesenchymal transition; EOC, epithelial ovarian cancer; ESCC, esophageal squamous cell carcinoma; HCC, hepatocellular carcinoma; LSCC, Laryngeal squamous cell carcinoma; MMP‐2, Matrix metalloproteinase 2; MMP‐9, Matrix metalloproteinase 9; OSCC, oral squamous cell carcinoma; PC, pancreatic cancer; PCa, prostate cancer; PI3K/ AKT, phosphatidylinositol‐3‐kinase/protein kinase B; TSCC, tongue squamous cell carcinoma; Wnt: Wingless/ Integrated