TABLE 2.
Univariate and multivariate analysis of prognostic factors in GIST for 5‐year overall survival rate
| Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| HR | p > |z| | 95% CI | HR | p > |z| | 95% CI | |||
|
FABP4 expression High vs. Low |
2.611 | <0.001* | 1.523 | 4.476 | 2.052 | 0.021* | 1.116 | 3.775 |
|
Age (years) ≤60 vs. >60 |
1.364 | 0.247 | 0.806 | 2.309 | ||||
|
Gender Male vs. Female |
0.901 | 0.695 | 0.536 | 1.516 | ||||
|
Tumor size (cm) 5 vs. 5–10 vs. ≥10 |
1.487 | 0.026* | 1.050 | 2.106 | ||||
|
Mitotic index (per 50 HPFs) 0–5 vs. 6–10 vs. >10 |
1.450 | 0.027* | 1.044 | 2.015 | ||||
|
Number of lesions Single vs. Multiple |
1.330 | 0.543 | 0.531 | 3.333 | ||||
|
Tumor location Stomach vs. intestine |
1.051 | 0.788 | 0.732 | 1.508 | ||||
|
AFIP‐Miettinen risk Very low–Moderate risk vs. High risk |
3.701 | <0.001* | 2.163 | 6.333 | 3.576 | <0.001* | 1.961 | 6.519 |
*p < 0.05.
Abbreviations: CI, confidence interval; FABP4, fatty acid‐binding protein 4; GIST, gastrointestinal stromal tumors; HPFs, high‐power fields.