Table 2a.
Genes of SCK-cryopreserved hiPS cells classified under ‘apoptosis’ with a difference in expression of more than 1.5-fold compared with the non-frozen hiPS cells.
| No. | Gene Symbol | Probe Set ID | control2_Signal | SCK_Signal | SCK_Signal Log Ratio | GO Biological Process Term | Pathway Name |
|---|---|---|---|---|---|---|---|
| 1 | BCL2A1 | 16812344 | 40.4 | 77.5 | 0.94 | apoptotic process//anti-apoptosis | Apoptosis_KEGG |
| 2 | BID | 16932008 | 309.5 | 587.0 | 0.92 | induction of apoptosis via death domain receptors//glial cell apoptotic process//positive regulation of apoptotic process//neuron apoptotic process | – |
| 3 | IKBKE | 16676592 | 92.0 | 164.2 | 0.84 | DNA damage response, signal transduction resulting in induction of apoptosis | Apoptosis_KEGG |
| 4 | PRKCA | 16837128 | 270.8 | 456.4 | 0.75 | apoptotic process//cell adhesion//induction of apoptosis by extracellular signals//negative regulation of glial cell apoptotic process | G_Protein_Signaling//Wnt_signaling//Calcium_regulation_in_cardiac_cells//Smooth_muscle_contraction |
| 5 | RASGRF2 | 16997688 | 76.4 | 128.0 | 0.74 | apoptotic process | – |
| 6 | BIRC3 | 16730522 | 36.5 | 61.0 | 0.74 | apoptotic process//anti-apoptosis | – |
| 7 | TAX1BP1 | 17044568 | 644.6 | 1059.6 | 0.72 | apoptotic process//anti-apoptosis | – |
| 8 | WT1 | 16737105 | 55.6 | 87.2 | 0.65 | induction of apoptosis//negative regulation of apoptotic process | – |
| 9 | FAIM | 16946207 | 103.5 | 160.1 | 0.63 | apoptotic process//anti-apoptosis | – |
| 10 | CAV1 | 17050578 | 229.5 | 354.3 | 0.63 | induction of apoptosis by extracellular signals//positive regulation of anti-apoptosis//positive regulation of extrinsic apoptotic signaling pathway//positive regulation of intrinsic apoptotic signaling pathway | Integrin-mediated_cell_adhesion_KEGG |
| 11 | API5 | 16737482 | 60.1 | 92.2 | 0.62 | apoptotic process//anti-apoptosis | – |
| 12 | AKAP13 | 16812871 | 88.4 | 135.5 | 0.62 | apoptotic process//induction of apoptosis by extracellular signals | – |
| 13 | STK17B | 16906733 | 92.1 | 139.3 | 0.60 | apoptotic process//induction of apoptosis | – |
| 14 | CASP6 | 16978959 | 136.6 | 204.5 | 0.58 | apoptotic process//induction of apoptosis//cellular component disassembly involved in apoptotic process | – |
| 15 | MLH1 | 16938899 | 469.8 | 700.4 | 0.58 | DNA damage response, signal transduction resulting in induction of apoptosis | Ovarian_Infertility_Genes |