Fig. 3.

Local control of bone metastases. a Local control of all bone metastatic bone lesions. b Primary tumor sites (favorable group vs. moderately unfavorable group vs. unfavorable group; favorable group: head and neck, lung/mediastinal, breast, gastric, gynecologic, prostate, bladder, and skin cancers; moderately unfavorable group: kidney/ureter and non-epithelial cancers; unfavorable group: esophageal, colorectal, and hepatobiliary/pancreatic cancers). c EBRT sites (vertebral bone vs. other bone). d EBRT dose (BED₁₀) (< 39.0 Gy vs. 39.0 Gy vs. > 39.0 Gy). BED Biologically effective dose, EBRT external beam radiotherapy