Fig. 2.

Generation of CAR-T Cells for immunotherapy. One form of adoptive cell therapy is CAR (Chimeric antigen receptors) T cell therapy. It is an accepted treatment procedure for both lymphomas and leukaemias. CAR T cell therapy is considered as a type of adoptive immune cell therapy where T cells are collected from a patient’s tumor sample, taken to a laboratory where the T-cell receptor is incorporated with tumor antigen-specific antibody receptor to get chimeric antigen receptor T (CAR T) cells. Nowadays MUC 1 and Glypican 3 targeting CAR-T cells are under clinical trial for different cancers