Table 1.
Clinical trials of drugs targeting tumor antigens
| Sl. no. | Tumor antigens | Types of cancer | Clinical trial details |
|---|---|---|---|
| 1 | Heat Shock Protein (HSP) | Colorectal cancer | NCT02324114 |
| Breast cancer | NCT02650193 | ||
| Squamous cell carcinoma | NCT04628806 | ||
| Leukaemia | NCT04437420 | ||
| 2 | Mitogen-activated protein kinase (MAPK) | Neoplasms | NCT01392521 |
| NSCLC | NCT01229150 | ||
| HCC | NCT01668017 | ||
| Ovarian cancer/NSCLC | NCT02607813 | ||
| 3 | Glypican-3(GPC3) | HCC | NCT04715191 |
| HCC | NCT03884751 | ||
| HCC | NCT03198546 | ||
| Advanced HCC | NCT03980288 | ||
| HCC | NCT02905188 | ||
| Lung Squamous Cell Carcinoma | NCT02876978 | ||
| HCC | NCT04121273 | ||
| 4 | Mucin 1 (MUC 1) | Advanced Esophageal Cancer | NCT03706326 |
| Metastatic Breast Cancer | NCT04020575 | ||
| Advanced Solid Tumor | NCT03179007 | ||
| Lung Neoplasm Malignant/Non-small Cell Lung Cancer | NCT03525782 | ||
| Gastric Cancer | NCT02602249 | ||
| 5 | Phosphoinositide-3- kinase (P13K) | Colorectal Cancer | NCT02945033 |
| Colon cancer | NCT03711058 | ||
| NSCLC | NCT01723800 | ||
| NSCLC | NCT02194049 | ||
| 6 | Human leukocyte antigen- G(HLA-G) | Leukaemia | NCT00075816 |
| Haematological Malignancies | NCT01246206 | ||
| Blood Cancer/ Multiple Myeloma | NCT00185614 | ||
| 7 | METADHERIN (MTDH) | Bladder cancer | NCT04286672 |