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. 2021 Nov 20;21:613. doi: 10.1186/s12935-021-02314-y

Table 2.

Difference of gene and pathway mutations with significance between iCAFs high and low groups of TCGA BLCA patients

Gene iCAFs high-wild iCAFs High-mutation iCAFs Low-wild iCAFs Low-mutation p-value
FGFR3 190 (96.45%) 7 (3.55%) 158 (77.45%) 46 (22.55%)  < 0.001
TP53 103 (52.28%) 94 (47.72%) 136 (66.67%) 68 (33.33%) 0.005
Pathways iCAFs high-affected iCAFs high-not affected iCAFs low-affected iCAFs low-not affected p-value
TP53 112 (56.85%) 85 (43.15%) 152 (74.51%) 52 (25.49%) < 0.001
RTK-RAS 106 (53.81%) 91 (46.19%) 86 (42.16%) 118 (57.84%) 0.025