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. 2021 Oct-Dec;13(4):176–182.

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Copyright© 2021 Avicenna Research Institute

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Figure 2. — In control group during DAPI staining, the intact nucleus showed that the cells were healthy. In the cisplatin and Fisetin groups, A2780 cells underwent apoptosis after 24 hr of treatment and the cell nuclei were fragmented, and the rate was higher in the combined group. AO/PI staining: The number of apoptotic (Red) cells in the combined group is higher than the groups treated with either cisplatin or Fisetin (Magnification×10). The results of Annexin V-FITC/PI assay show that in the combined group, induction of apoptosis in cells under treatment was much more effective than the use of either Fisetin or cisplatin.