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Pathological assessment after transplantation of LV-VEC.hBDD-FVIII HA BOECs into the Cell Pouch device
(A) Sernova Cell Pouches were removed at 4, 8, or 12 weeks and stained by H&E and Masson's trichrome for blinded histopathological analysis. Histology scores and representative images at 12 weeks post-transplant with 10 × 106 LV-VEC.hBDD-FVIII BOECs (animal groups n = 2–3). (B) Quantification of H&E and Masson's trichrome for blinded histopathological analysis.
