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. 2021 Nov 8;12:736301. doi: 10.3389/fphar.2021.736301

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Copyright © 2021 Zhan, Deng, Wu, Xu, Wang, Li and Pan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Images of live/dead fluorescent staining of BMSCs cells on the PLLA, PLLA/LC, and HAP-PLLA/LC composites after culturing for 1, 3, and 5 days. (B) CLSM micrographs of BMSCs stained with rhodamine-conjugated phalloidin (red) and 4, 6-diamidino-2-phenylindole (DAPI) (blue) were cultured on the PLLA, PLLA/LC, and HAP- PLLA/LC composites for 1 day. (C) The cell growth curve of BMSCs. (D,E) The results of Ki67 protein expression on day 5 (*p < 0.05 and **p < 0.01).