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. 2021 Nov 8;8:752875. doi: 10.3389/fmed.2021.752875

Figure 1.

Figure 1

Development of ACLF in different stages of liver disease. ACLF can develop directly in patients with chronic liver disease (CLD), compensated and decompensated cirrhosis or it may progress slowly from CLD to compensated and decompensated cirrhosis and eventually develop into ACLF. However, development of ACLF in patients with compensated and decompensated cirrhosis inflict higher risk of mortality.