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. 2021 Nov 8;9:743910. doi: 10.3389/fcell.2021.743910

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Copyright © 2021 Shen, Wang, Qiu, Li, Wang, Xue and Tang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Autophagy-related DEGs of HCC in ICGC and TCGA. (A,C) Heat maps of DEGs in ICGC and TCGA. The number of normal tissues was 202, and the number of tumor tissues was 243, all retrieved from ICGC. As for TCGA, the number of normal samples was 50 and that of tumor samples was 374. (B,D) Volcano plots of DEGs in the ICGC and TCGA databases. Ten hub genes studied in our research were labeled in the corresponding position. The detailed analytic information of the autophagy-related genes is presented in Supplementary Tables 1, 2.