Table 1.
Patients’ demographic characteristics.
| Patients | 30 |
| Median age, years (range) | 81 (36–95) |
| Sex | |
| Male | 24 (80%) |
| famale | 6 (20%) |
| ECOG performance status | |
| 0 | 7 (23.3%) |
| 1 | 17 (56.7%) |
| 2 | 6 (20%) |
| Primary cutaneous squamous cell carcinoma (CSCC) site | |
| Head or neck | 23 (76.7%) |
| Limbs | 5 (16.7%) |
| Ubiquitous skin lesions | 2 (6.7%) |
| Previous chemotherapy for CSCC | 3 (10%) |
| Previous radiotherapy for CSCC | 10 (33.3%) |
| Previous surgery for CSCC | |
| 0–1 surgery | 15 (50%) |
| 2–4 surgeries | 7 (23.3%) |
| More than five surgeries | 8 (26.7%) |
| Histological differentiation of tumor | |
| Well differentiated | 4 (13.3%) |
| Moderately differentiated | 12 (40%) |
| Poorly differentiated | 10 (33.3%) |
| Unknown | 4 (13.3%) |
| Locally advanced CSCC | 25 (83.3%) |
| Metastatic cutaneous CSCC | 5 (16.7%) |
| Immunosuppressive conditions a | 5 (16.7%) |
| Main comorbidities | |
| Cardiovascular | 20 (66.7%) |
| Metabolic | 5 (16.7%) |
| Respiratory | 6 (20%) |
| Mental disorders | 3 (10%) |
| Frailty score | |
| Not frail | 5 (16.7%) |
| Frail | 25 (83.3%) |
| Charlson Comorbidity Index | |
| 0 | 6 (20%) |
| 1 | 8 (26.7%) |
| 2 | 7 (23.3%) |
| 3 | 5 (16.7%) |
| 4 | 2 (6.7%) |
| 5 | 1 (3.3%) |
Data are n (%), unless otherwise specified.
a
Three patients with lymphoproliferative disease and two patients receiving immunosuppressive therapy.