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. 2021 Nov 8;12:698849. doi: 10.3389/fimmu.2021.698849

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Copyright © 2021 Ferreira-Gomes, Wich, Böde, Hube, Jacobsen and Jungnickel

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Graphical Abstract — Upon MyD88- and TLR-mediated recognition of C. albicans hyphae, but not yeasts, murine B cells show an increased activation (CD86 and AID) and secretion of IgG1 as well as IL-6, which promotes TH17 differentiation. The figure was created with Biorender.com.