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RNA-Seq analysis of canine transitional cell carcinoma (cTCC) tumours and normal bladder. (A) Principal component analysis of normalized gene counts. (B) 1219 and 1347 genes up-(red) and down-regulated (blue) in TCC tumour relative to normal bladder (logFC >2 and adj. p < 0.05). (C) Gene sets significantly enriched in tumour and normal (FDR q-val < 0.05). (D) Gene set enrichment analysis (GSEA) enrichment plots for significantly enriched gene sets
