Table 2.
Baseline characteristics of exosomal AHCY high and low expression in HBV-LC group.
| Variables | Total | Exosomal AHCY high expression | Exosomal AHCY low expression | P |
|---|---|---|---|---|
| (n = 141) | (n = 76) | (n = 65) | ||
| Age (years) | 54.06 ± 11.99 | 53.29 ± 11.56 | 54.95 ± 12.50 | 0.413 |
| Gender (M/F) | 79/62 | 40/36 | 39/26 | 0.380 |
| WBC (109/L) | 7.0 (4.9–11.1) | 8.0 (5.7–11.4) | 6.6 (3.6–10.3) | 0.038 |
| Hb (g/L) | 110 (89–126) | 116 (95–133) | 107 (80–123) | 0.044 |
| PLT (×109/L) | 70 (42–114) | 62 (35–104) | 80 (53–120) | 0.044 |
| ALT (U/L) | 79 (40–164) | 103 (54–178) | 62 (28–127) | 0.004 |
| AST (U/L) | 103 (56–177) | 118 (72–231) | 72 (32–152) | <0.001 |
| TBIL (μmol/L) | 178.0 (50.5–388.0) | 296.0 (146.8–472.8) | 52.0 (19.0–201.5) | <0.001 |
| DBIL (μmol/L) | 190.9 (53.8–299.5) | 253.5 (143.4–354.6) | 55.0 (17.5–216.5) | <0.001 |
| ALB (g/L) | 30.00 ± 5.44 | 29.31 ± 5.38 | 30.81 ± 5.43 | 0.104 |
| BUN (mmol/L) | 10.40 (5.56–18.16) | 11.82 (7.29–18.75) | 8.60 (5.05–15.85) | 0.072 |
| Cr (μmol/L) | 103 (72–182) | 119 (76–194) | 94 (70–128) | 0.062 |
| UA (μmol/L) | 283 (174–468) | 289 (182–491) | 273 (164–446) | 0.604 |
| INR | 1.84 (1.41–2.43) | 2.18 (1.83–2.64) | 1.46 (1.22–1.84) | <0.001 |
| PT (s) | 21.6 (16.8–27.8) | 25.3 (21.5–31.8) | 17.1 (14.5–21.1) | <0.001 |
| BA | 50 (28–77) | 51 (28–80) | 46 (28–74) | 0.457 |
| AFP (ng/ml) | 69.5 (12.0–161.8) | 73.0 (18.2–170.4) | 65.6 (5.6–153.1) | 0.375 |
| PCT | 1.29 (0.58–2.44) | 1.16 (0.69–2.16) | 1.57 (0.42–2.63) | 0.791 |
| ESR | 14 (6–29) | 13 (5–29) | 17 (7–29) | 0.618 |
| CRP (mg/L) | 21.5 (11.2–69.2) | 21.6 (13.2–64.7) | 19.3 (9.0–78.8) | 0.513 |
| MELD score | 77.18 ± 8.33 | 82.23 ± 5.77 | 71.28 ± 6.88 | <0.001 |
| Child-Pugh | 10 (9–11) | 11 (10–12) | 9 (7–10) | <0.001 |