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. 2021 Nov 8;12:761763. doi: 10.3389/fphar.2021.761763

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Copyright © 2021 Wei, Liu, Zhang, Liu, Yan, Wen and Tian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kinetics of formation of Sorafenib N-oxide in female (A) and male (B) liver microsomes. Data represent the means ± SD of six independent experiments in duplicate determinations.