Table 2.

Description of cytokines and chemokines for CAR-T cells profiling.

Soluble cytokines and chemokines categories
Effector	Stimulatory	Regulatory	Inflammatory	Chemoattractive
granzyme-B, IFN-gamma, MIP-1alpha, perforin, TNF-alpha, TNF-beta	GM-CSF, IL-2, IL-5, IL-7, IL-8, IL-9, IL-12, IL-15, IL-21	IL-4, IL-10, IL-13, IL-22, TGF-beta1, sCD137, sCD40L	IL-1B, IL-6, IL-17A, IL-17F, MCP-1, MCP-4	CCL-11, IP-10, MIP-1beta, RANTES

GM-CSF: Granulocyte-macrophage colony-stimulating factor; IL: Interleukin; TGF-Beta1: Transforming growth factor beta 1; MCP: Monocyte chemoattractant protein; CCL11: C-C Motif chemokine ligand 11; IP-10: Interferon gamma-induced protein 10; MIP: Macrophage inflammatory protein; RANTES: Regulated upon Activation, Normal T-cell Expressed, and Secreted.