Table 3.
Main characteristics of the studies included. Patients treated with EUS-guided EA technique. NA: not applicable, EA: etanol ablation, EUS: endoscopic ultrasound.
| Study population | Country | No. of patients with insulinoma | Gender (M\F) | Age (y) | Indication for EUS-EA | No of insulinomas | No of sessions | No of passes | Ethanol concentration (%) | Ethanol volume (ml) | Glucose (mmol/L) | Insulin (pmol/L) | C-peptid (pmol/L) | Type of adverse event | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| before EA | after EA | before EA | after EA | before EA | after EA | ||||||||||||
| Luo et al. 37 | China | 1 | M | 32 | comorbidity | 1 | 1 | NA | 99 | 1.5 | NA | NA | NA | NA | NA | NA | no |
| Mittal et al. 16 | USA | 1 | M | 59 | unresectable | 1 | 2 | 2 | NA | 2.8 | NA | NA | NA | NA | NA | NA | no |
| Mosquera-Klinger et al. 38 | Colombia | 2 | F | 40 | refuse surgery | 1 | 1 | 2 | 96 | 2 | 2 | NA | NA | NA | NA | NA | no |
| F | 80 | comorbidity | 1 | 1 | 2 | 96 | 2 | NA | NA | NA | NA | NA | NA | no | |||
| Nelson et al. 39 | USA | 1 | F | 81 | comorbidity | 1 | 1 | NA | 98 | 1 | NA | NA | NA | NA | NA | NA | no |
| Paik et al. 41 | Korea | 3 | M | 99 | refuse surgery | 1 | 1 | NA | NA | 1.2 | NA | NA | NA | NA | NA | NA | no |
| M | 20 | refuse surgery | 1 | 1 | 2.5 | no | |||||||||||
| M | 32 | refuse surgery | 1 | 1 | 3 | abd.pain | |||||||||||
| Park et al. 42 | Korea | 2 | F | 66 | refuse surgery | 1 | 2 | 2 | 99 | 6.4 | NA | NA | NA | NA | NA | NA | no |
| F | 27 | comorbidity | 3 | 1 | 3 | 99 | 3.2 | no | |||||||||