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Virulence level of different bacterial strains as depicted in mouse infection model. Survival of mice (n = 8) infected by 2 × 105 CFU (A) and 1 × 106 CFU (B) of each K. pneumoniae strain at 168 h. The test strains included K. pneumoniae strain SH12, its virulence plasmid cured strain PC_SH12, CR-HvKP strain CR-HvKP4 (hypervirulence control), and the classic CRKP strain FJ8 (low virulence control).
