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. 2021 Nov 8;9:703836. doi: 10.3389/fcell.2021.703836

FIGURE 2.

FIGURE 2

Gene expression pattern of effector genes related with WNT, FGF, BMP signaling in the ANZ and PNZ. Cell death pattern and in situ hybridizations of (A) Mkp3, Fgfr1, Fgfr2, Fgfr3, Bmp4, Bmp7, Bambi, Msx2, Dkk, and Wif. They were evaluated in the anterior margin of the limb at developing stage 24 HH. (A) Mkp3, Fgfr1, Fgfr2, and Fgfr3 are genes related to FGF signaling. (B) Bmp4, Bmp7, Bambi, and Msx2 related to BMP signaling, whereas (C) Dkk, Wif, related to WNT signaling. Notice the dynamic expression of all genes in the ANZ.