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Ligand-independent neurite formation in PC12nnr5 cells transfected with TrkA mutant receptors. Neurite outgrowth was quantified 3 days after transfection by assessing the percentage of β-galactosidase-positive cells bearing neurites at least twice the length of their cell bodies. Results were normalized to the trk-5 oncogene response (set at 100%). Values were calculated from at least five independent experiments. Means and standard deviations (SD) are shown.
