Figure 5.

Morphological pattern of aortic valve stenosis (aortic stenosis/AS) and reversibility upon TAVR

(A) Preprocessing and data analysis steps and retained number of features in each step (∗, reversible after TAVR).

(B) Venn-like diagram of substance-specific and AS-specific features. AS-specific TAVR-reversible features are counted separately and highlighted in lime. Overlaps within substance-specific features are not shown.

(C) Heatmap of model-predicted batch-corrected differential morphological features (hierarchical clustering, ward.D2).

(D) Radar plots show differentially regulated meta-features for AS and TAVR. Data are shown for 3 independent experiments.