Table 1.
International Society on Thrombosis and hemostasis and sepsis-induced coagulopathy scoring systems for disseminated intravascular coagulopathy diagnosis
| Items | ISTH | SIC | Points |
|---|---|---|---|
| Platelet count (×109/L) | ≥100 | ≥150 | 0 |
| 50-100 | 100-150 | 1 | |
| <50 | <100 | 2 | |
| D-Dimer elevation or FDP elevation (mg/L) | <2 times ULN | - | 0 |
| 2-4 times ULN | - | 2 | |
| >4 times ULN | - | 3 | |
| <10 | - | 0 | |
| 10-25 | - | 2 | |
| >25 | - | 3 | |
| PT prolongation (s)/INR increase | <3 | <1.2 | 0 |
| 3-6 | 1.2-1.4 | 1 | |
| ≥3 | ≥1.4 | 2 | |
| Fibrinogen (g/L) | >1 | - | 0 |
| <1 | - | 1 | |
| SOFA score | - | 0 | 0 |
| - | 1 | 1 | |
| - | ≥2 | 2 |
Overt DIC: ISTH score ≥5, early stages of DIC: SIC score ≥4. DIC=Disseminated intravascular coagulopathy; ISTH=International Society on Thrombosis and hemostasis; SIC=Sepsis-induced coagulopathy; FDP=Fibrin degradation products; PT=Prothrombin time; INR=International normalized ratio; SOFA=Sequential organ failure assessment