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. Author manuscript; available in PMC: 2021 Nov 22.
Published in final edited form as: Biomaterials. 2021 Jun 30;276:120989. doi: 10.1016/j.biomaterials.2021.120989

Fig. 2. In vivo administration of BDNF AntagoNAT (AT) core-shell implant by MIND technique to the submucosal space of naïve Sprague Dawley rats.

Fig. 2.

(A) Exposure of nasal bones after the elevation of bilateral skin flaps post-midline sagittal incision. (B) High speed drill-aided removal of nasal bone for formation of a subcutaneous cavity within the submucosal space. (C) Placing BDNF AT core-shell implant within the cavity. (D) Closure of skin incision with nylon sutures.