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Pharmacokinetic parameters of BDNF response following BDNF AT implant administration via MIND technique.
| Parameter | Unit | Olfactory bulb | Striatum | Hippocampus | Substantia nigra | Cerebellum |
|---|---|---|---|---|---|---|
| t max | day | 14 | 14 | 14 | 14 | 7 |
| C max | Pg*μg protein − 1 | 1.16 | 1.01 | 1.26 | 1.35 | 1.25 |
| AUEC a | pg*μg protein − 1 *day | 15.0 | 13.8 | 17.4 | 18.0 | 18.9 |
Estimated from time zero to last time point.
