Table 3.

Correlation of the sex-specific biomarkers and the acute respiratory distress syndrome (ARDS) stage in the COVID-19 patients

Admission biomarkers for female patients
Moderate / severe ARDS (at admission)	Deteriorated ARDS (during hospitalization)
↓ Lymphocytes counts	↑ Neutrophil counts
↑ Neutrophil counts	↑ D-Dimer plasma levels
↑ Ferritin plasma levels	↑ Ferritin plasma levels
	↓ Ang1-7 plasma levels

Admission biomarkers for male patients
Moderate / severe ARDS (at admission)	Deteriorated ARDS (during hospitalization)
↓ Lymphocytes counts	↓ Lymphocytes counts
↑ Ferritin plasma levels	↑ D-Dimer plasma levels
↑ D-Dimer plasma levels	↑ Ferritin plasma levels
↓ Testosterone plasma levels	↓ Testosterone plasma levels

Biomarkers specific only for female or male patients are indicated in bold