TABLE 2.
Stabilities of peptides in rat plasma.
| Peptide name | Input (NT) | Immediately after mixing | Incubation time 24 h |
|---|---|---|---|
| VIpep-3 | 1299273 | 900813 | 95354 |
| 100% | 10.6% | ||
| KS-132 | 1460241 | 1206247 | 696652 |
| 100% | 57.8% | ||
| KS-133(monocyclic) | 768775 | 744262 | 724176 |
| 100% | 97.3% | ||
| KS-133 | 161695 | 165254 | 163537 |
| 100% | 99.0% |
Peak area values obtained by RP-HPLC and the residual rate (%) are listed.
NT indicates no plasma treatment.