TABLE 3.
Inhibitors | Category | Pathways | IC50 |
---|---|---|---|
FPA124 | Kinase inhibitors | Akt | 42.13 |
10‐DEBC hydrochloride | mTOR/Akt | 11.63 | |
API‐2 | Akt | 0.88 | |
AG490 | JAK2/STAT | 21.10 | |
ZM449829 | STAT5 | 12.78 | |
Thioridazine hydrochloride | Stem cell modulator | mTOR/Akt/PI3K | 10.42 |
KU55933 | Epigenome | mTOR | 29.33 |
L002 | STAT3 | 10.4 | |
Mitoxantrone | Topoisomerase II inhibitor | Antineoplastic agent | 0.36 |
Doxorubicin | Anthracycline | 0.24 | |
Ruxolitinib | Kinase inhibitors | JAK1 and JAK2 | 0.94 |