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. 2021 Nov 22;2021(11):CD004407. doi: 10.1002/14651858.CD004407.pub5

ba‐Liese 2013.

Study characteristics
Methods Case‐control study ‐ Munich, Bavaria, Germany
Participants Children at least 1 year of age, born on or after 1 July 2003, residing in Germany
Cases: suspected clinical varicella disease at the time of study entry
Control: children matched by age and paediatric practice, fulfilling the same criteria as cases but without history or present clinical diagnosis of varicella
Interventions Cases were classified as vaccinated varicella cases if they had received OKA/GSK, OKA/Merck, or the combined MMR‐OKA/GSK vaccine at least 28 days before varicella onset.
Controls were classified as vaccinated if they had received OKA/GSK, OKA/Merck, or MMR‐OKA/GSK vaccine at least 28 days before varicella onset in the matched case.
Outcomes Laboratory or clinically confirmed
Funding Source Pharmaceutical industry
Notes Ascertainment of the vaccination status by practice record and vaccination cards
Risk of bias
Bias Authors' judgement Support for judgement
CCS ‐ case selection Low risk Adequate ‐ laboratory‐confirmed ‐ representative series of case
CCS ‐ control selection Low risk Adequate ‐ community
CCS ‐ comparability Low risk Adequate ‐ matched by age and paediatric practice
CCS ‐ exposures Low risk Adequate ‐ secure record‐ vaccination card
Summary Risk of Bias assessment Low risk We had concerns regarding multiple domains such that our confidence in the result is substantially lowered.