ba‐Liese 2013.
Study characteristics | ||
Methods | Case‐control study ‐ Munich, Bavaria, Germany | |
Participants | Children at least 1 year of age, born on or after 1 July 2003, residing in Germany Cases: suspected clinical varicella disease at the time of study entry Control: children matched by age and paediatric practice, fulfilling the same criteria as cases but without history or present clinical diagnosis of varicella |
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Interventions | Cases were classified as vaccinated varicella cases if they had received OKA/GSK, OKA/Merck, or the combined MMR‐OKA/GSK vaccine at least 28 days before varicella onset. Controls were classified as vaccinated if they had received OKA/GSK, OKA/Merck, or MMR‐OKA/GSK vaccine at least 28 days before varicella onset in the matched case. |
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Outcomes | Laboratory or clinically confirmed | |
Funding Source | Pharmaceutical industry | |
Notes | Ascertainment of the vaccination status by practice record and vaccination cards | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
CCS ‐ case selection | Low risk | Adequate ‐ laboratory‐confirmed ‐ representative series of case |
CCS ‐ control selection | Low risk | Adequate ‐ community |
CCS ‐ comparability | Low risk | Adequate ‐ matched by age and paediatric practice |
CCS ‐ exposures | Low risk | Adequate ‐ secure record‐ vaccination card |
Summary Risk of Bias assessment | Low risk | We had concerns regarding multiple domains such that our confidence in the result is substantially lowered. |