| Study characteristics |
| Methods |
Case‐control study ‐ part of a wider epidemiologic study aimed at assessing the incidence, prevalence, and clinical expression of IBD in Vukovar‐Srijem County (population in 2001: 204,768), a lesser developed part of continental Croatia that has experienced deep demographic changes in the recent past. |
| Participants |
There were 119 UC patients and 31 CD patients of a total of 150 patients in the cohort. A total of 150 individuals, volunteers, not having a diagnosis of IBD, age and sex matched, were used as the control group. Information on examined risk factors was obtained from all participants in a previously conducted interview. Patients were contacted personally or by phone and interviewed by a gastroenterologist. |
| Interventions |
MMR vaccination |
| Outcomes |
IBD patients were identified according to the hospital’s patient records. |
| Funding Source |
Government |
| Notes |
MMR vaccination rates were higher in CD patients (90.3%) compared to UC patients and the controls (74.8% and 67.3%, respectively) (P = 0.026). |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| CCS ‐ case selection |
Low risk |
Probably adequate ‐ insufficient information |
| CCS ‐ control selection |
High risk |
Probable selection bias ‐ insufficient information ‐ recruited on a voluntary basis |
| CCS ‐ comparability |
High risk |
Not adequate statistical methods |
| CCS ‐ exposures |
Unclear risk |
Probable information bias ‐ insufficient information |
| Summary Risk of Bias assessment |
High risk |
We had concerns regarding multiple domains such that our confidence in the result is substantially lowered. |
