ca‐Arenz 2005.
Study characteristics | ||
Methods | Cohort study ‐ Germany | |
Participants | 55 families and 43 children. Household contacts in families with at least 1 mumps case. 43 exposed children included in the final analysis, of which 25 were female and 18 were male. Median age was 5 years 3 months in measles cases and 6 years 6 months in contacts without measles. None of the included children had a history of measles. |
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Interventions | Vaccination with measles‐containing vaccine | |
Outcomes | Case definition: generalised maculopapular rash with fever 38.4 °C for 3 days and at least 1 of the following signs: cough, coryza, Koplik spots, or conjunctivitis. Primary case: the first household member who acquired measles. Co‐primary cases were defined as measles patients who developed a fever within 4 days after the onset of a rash in the primary case. Secondary cases were confirmed measles patients who developed a fever within 5 to 25 days after the onset of a rash in the primary case. Contacts were all household members who had contact with measles cases in the household during their infectious period. |
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Funding Source | Government | |
Notes | Insufficient information about vaccine composition (if MMR or bivalent) for household contact study. Screening method was used for vaccine effectiveness assessment in Coburg school population aged older than 5 years. Many important details are missing. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
PCS/RCS ‐ exposed cohort selection | Unclear risk | There was insufficient information. |
PCS/RCS ‐ non‐exposed cohort selection | Unclear risk | There was insufficient information. |
PCS/RCS ‐ comparability | Unclear risk | The cohort was limited to affected classes. |
PCS/RCS ‐ assessment of outcome | Unclear risk | There was insufficient information. |
Summary Risk of Bias assessment | High risk | We had concerns regarding multiple domains such that our confidence in the result is substantially lowered. |