Sorup 2019.
Methods | Cohort study |
Participants | 295,559 children born in Denmark from April 2004 to December 2010. The cohort were followed from age 47 months (1 month before turning age 4 years, which is the recommended age of the second MMR (MMR‐2)) until age 60 months. |
Interventions | MMR vaccination second dose |
Outcomes | Antibiotic prescriptions and hospital admissions for any off‐targeted infection |
Notes | Conclusion: in this study, revaccination with MMR appeared safe with regard to off‐target infections and was associated with a lower rate of severe off‐target infections. More studies of the possible association between revaccination with live attenuated vaccines and off‐target infections are needed. |
AEFI: adverse events following immunisation CI: confidence interval HAEs: hypersensitivity‐type adverse events MMR: measles, mumps, rubella vaccine OR: odds ratio PEP: postexposure prophylaxis