Table 1. Patient characteristics.
Statistics presented as mean ± SD, median [P25, P75], N (column %).
p-values: at-test, bWilcoxon rank sum test, cPearson's chi-square test, dSatterthwaite t-test. BMI: body mass index; GI: gastrointestinal.
| Factor | Overall (N=97) | Early stage (N=68) | Advanced stage (N=29) | p-value |
| Age at diagnosis (years) | 65.8 ± 9.6 | 66.8 ± 9.4 | 63.3 ± 9.9 | 0.11a |
| Male Gender | 83 (85.6) | 57 (83.8) | 26 (89.7) | 0.45c |
| White race | 91 (93.8) | 64 (94.1) | 27 (93.1) | 0.85c |
| Current/former smoker | 70 (72.2) | 48 (70.6) | 22 (75.9) | 0.60c |
| If smoker; pack years | 25.1 ± 14.4 | 25.5 ± 14.8 | 24.1 ± 14.0 | 0.73a |
| History of alcohol use | 5 (8.5) | 2 (5.0) | 3 (15.8) | 0.16c |
| Never/quit alcohol | 12 (12.4) | 9 (13.2) | 3 (10.3) | 0.77c |
| BMI (kg/m2) at diagnosis | 27.0 ± 6.5 | 28.8 ± 6.4 | 22.8 ± 4.4 | <0.001d |
| Hemoglobin (gm/dL) | 13.8 ± 1.9 | 13.6 ± 2.0 | 14.2 ± 1.7 | 0.25a |
| Dysphagia | 38 (39.2) | 21 (30.9) | 17 (58.6) | 0.010c |
| Odynophagia | 1 (1.03) | 1 (1.5) | 0 (0.00) | 0.51c |
| Heartburn/regurgitation | 36 (37.1) | 24 (35.3) | 12 (41.4) | 0.57c |
| Chest pain | 7 (7.2) | 5 (7.4) | 2 (6.9) | 0.94c |
| Post prandial distress | 10 (10.3) | 7 (10.3) | 3 (10.3) | 0.99c |
| Unintentional weight loss | 23 (23.7) | 12 (17.6) | 11 (37.9) | 0.032c |
| Weight loss (lbs.) | 15.0 [10.0, 26.0] | 24.5 [10.0, 26.0] | 10.0 [10.0, 15.0] | 0.44b |
| GI bleeding at presentation | 19 (19.6) | 15 (22.1) | 4 (13.8) | 0.35c |
| Prior diagnosis of Barrett’s esophagus | 68 (70.1) | 51 (75.0) | 17 (58.6) | 0.11c |